生物素Anti-CX3CR1抗体[2A9-1] (ab95620)
Key features and details
- Biotin Rat monoclonal [2A9-1] to CX3CR1
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG2b
概述
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产品名称
生物素Anti-CX3CR1抗体[2A9-1]
参阅全部 CX3CR1 一抗 -
描述
生物素大鼠单克隆抗体[2A9-1] to CX3CR1 -
宿主
Rat -
偶联物
Biotin -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
CX3CR1-EGFP fusion protein.
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阳性对照
- Normal Human peripheral blood cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.09% Sodium azide -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
2A9-1 -
同种型
IgG2b -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95620于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 0.25µl for 105-8 cells.
Use a final volume of 100µl.
ab18542 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|
说明 |
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Flow Cyt
Use 0.25µl for 105-8 cells. Use a final volume of 100µl.
ab18542 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|
靶标
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功能
Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. -
组织特异性
Expressed in lymphoid and neural tissues. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1524 Human
- Omim: 601470 Human
- SwissProt: P49238 Human
- Unigene: 78913 Human
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别名
- Beta chemokine receptor-like 1 antibody
- C X3 C CKR 1 antibody
- C-X3-C CKR-1 antibody
see all
图片
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Staining of normal Human peripheral blood cells with 0.125µg/100µl rat IgG1 isotype control Biotin (left) or 0.125µg/100µl ab95620 (right), followed by Streptavidin PE.
Samples were subsequently stained intracellularly with an anti Human Perforin FITC. Cells were gated on CD16+CD56+ using anti-CD16 eFluor 450 and anti-CD56 APC antibodies.
数据表及文件
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Datasheet download
文献 (1)
ab95620 被引用在 1 文献中.
- Sun C et al. ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma. Int J Oncol 57:249-263 (2020). PubMed: 32319605