Anti-CTDSP2抗体[2230C1a] (ab50621)

概述

  • 产品名称
    Anti-CTDSP2抗体[2230C1a]
    参阅全部 CTDSP2 一抗
  • 描述
    小鼠单克隆抗体[2230C1a] to CTDSP2
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to near the N terminal amino acids 21-124 of Human CTDSP2

  • 阳性对照
    • recombinant human CTDSP2 fragment

性能

应用

Our Abpromise guarantee covers the use of ab50621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100. Detects a band of approximately 35 kDa (predicted molecular weight: 31 kDa).
Dot blot 1/100.

靶标

  • 功能
    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
  • 组织特异性
    Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
  • 序列相似性
    Contains 1 FCP1 homology domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
    • conserved gene amplified in osteosarcoma 4 antibody
    • conserved gene amplified in osteosarcoma antibody
    • CTDS2_HUMAN antibody
    • Ctdsp2 antibody
    • NIF2 antibody
    • NLI interacting factor 2 antibody
    • NLI-interacting factor 2 antibody
    • Nuclear LIM interactor interacting factor 2 antibody
    • Nuclear LIM interactor-interacting factor 2 antibody
    • OS4 antibody
    • Protein OS 4 antibody
    • Protein OS-4 antibody
    • PSR2 antibody
    • SCP2 antibody
    • Small C-terminal domain phosphatase 2 antibody
    • Small CTD phosphatase 2 antibody
    see all

图片

实验方案

文献

ab50621 has not yet been referenced specifically in any publications.

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