Anti-CTDSP1抗体- C-terminal (ab76099)

概述

  • 产品名称Anti-CTDSP1抗体- C-terminal
    参阅全部 CTDSP1 一抗
  • 描述
    兔多克隆抗体to CTDSP1 - C-terminal
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    KLH conjugated synthetic peptide selected from the C terminal region of human CTDSP1 protein.

  • 阳性对照
    • CEM tissue lysate. 293 cell lysates transiently transfected with the CTDSP1 gene. Human hepatocarcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab76099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • 组织特异性Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
  • 序列相似性Contains 1 FCP1 homology domain.
  • 细胞定位Nucleus. Colocalizes with RNA polymerase II.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody
    • CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 antibody
    • CTDS1_HUMAN antibody
    • CTDSP1 antibody
    • NIF3 antibody
    • NLI IF antibody
    • NLI interacting factor 3 antibody
    • NLI-IF antibody
    • NLI-interacting factor 3 antibody
    • NLIIF antibody
    • Nuclear LIM interactor interacting factor 3 antibody
    • Nuclear LIM interactor-interacting factor 3 antibody
    • SCP1 antibody
    • Small C-terminal domain phosphatase 1 antibody
    • Small CTD phosphatase 1 antibody
    see all

Anti-CTDSP1 antibody - C-terminal 图像

  • Anti-CTDSP1 antibody - C-terminal (ab76099) at 1/100 dilution + CEM tissue lysate at 12.5 µg

    Predicted band size : 29 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 25 kDa,60 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-CTDSP1 antibody - C-terminal (ab76099) at 1/100 dilution

    Lane 1 : Nontransfected 293 cell lysates
    Lane 2 : 293 cell lysates transiently transfected with the CTDSP1 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 29 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 72 kDa. We are unsure as to the identity of these extra bands.
  • ab76099, at 1/50 dilution, staining CTDSP1 in formalin-fixed, paraffin-embedded human hepatocarcinoma tissue by Immunohistochemistry, followed by a peroxidase conjugated secondary antibody and DAB staining.

Anti-CTDSP1 antibody - C-terminal (ab76099)参考文献

ab76099 has not yet been referenced specifically in any publications.

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