Anti-CRYZ抗体[2A9DD1] (ab110310)

概述

  • 产品名称
    Anti-CRYZ抗体[2A9DD1]
    参阅全部 CRYZ 一抗
  • 描述
    小鼠单克隆抗体[2A9DD1] to CRYZ
  • 经测试应用
    适用于: ICC/IF, IP, In-Cell ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue, cells or virus corresponding to CRYZ. Human liver mitochondria.

  • 阳性对照
    • HeLa cells; Human liver and HepG2 lysates.
  • 常规说明

    This antibody clone is manufactured by Abcam.

    Product was previously marketed under the MitoSciences sub-brand.

性能

应用

Our Abpromise guarantee covers the use of ab110310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 2 µg/ml. For 2 hours.
IP Use at an assay dependent dilution.
In-Cell ELISA Use at an assay dependent concentration.

靶标

  • 功能
    Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
  • 组织特异性
    Only very low amounts in the lens.
  • 序列相似性
    Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Crystallin zeta (quinone reductase) antibody
    • Crystallin zeta antibody
    • Cryz antibody
    • DKFZp779E0834 antibody
    • FLJ41475 antibody
    • NADPH:quinone reductase antibody
    • QOR_HUMAN antibody
    • Quinone oxidoreductase antibody
    • Zeta crystallin antibody
    • Zeta-crystallin antibody
    see all

Anti-CRYZ antibody [2A9DD1] 图像

  • Immunocytochemistry analysis using ab110310 at 2µg/ml staining CRYZ in HELa cells (4% paraformaldehyde fixed and 0.1% Triton X-100 permeabilized) followed by Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1 hour (green).
  • Using MitoSciences' standard immunoprecipitation protocol, ab110310 precipitates the 35kDa CRYZ protein from human liver and HepG2 lysate. Identity of this protein was confirmed by mass spectrometry. This gel was stained with silver nitrate.

Anti-CRYZ antibody [2A9DD1] (ab110310)参考文献

ab110310 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110310.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册