概述

  • 产品名称Anti-CRYBB3抗体
    参阅全部 CRYBB3 一抗
  • 描述
    小鼠单克隆抗体to CRYBB3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性

    预测可用于: Human
  • 免疫原

    Recombinant fragment: PHHKLHLFEN PAFSGRKMEI VDDDVPSLWA HGFQDRVASV RAINGTWVGY EFPGYRGRQY VFERGEYRHW NEWDASQPQL QSVRRIRDQK WHKRGRFPSS , corresponding to amino acids 112-212 of Human CRYBB3, with tag (NP_004067)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab76642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 24 kDa.
    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Crystallins are the dominant structural components of the vertebrate eye lens.
    • 疾病相关Defects in CRYBB3 are the cause of cataract congenital nuclear autosomal recessive type 2 (CATCN2) [MIM:609741]. A congenital cataract affecting the central nucleus of the eye. Nuclear cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders.
    • 序列相似性Belongs to the beta/gamma-crystallin family.
      Contains 4 beta/gamma crystallin 'Greek key' domains.
    • 结构域Has a two-domain beta-structure, folded into four very similar Greek key motifs.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Beta B3 crystallin antibody
      • Beta crystallin B3 antibody
      • Beta-B3 crystallin antibody
      • Beta-crystallin B3 antibody
      • CRBB3_HUMAN antibody
      • CRYB3 antibody
      • Crybb3 antibody
      see all

    Anti-CRYBB3 antibody 图像

    • Anti-CRYBB3 antibody (ab76642) at 5 µg/ml + immunogen at 0.2 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

      Predicted band size : 24 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)

    Anti-CRYBB3 antibody (ab76642)参考文献

    ab76642 has not yet been referenced specifically in any publications.

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