概述

  • 产品名称Anti-CRTAM抗体
    参阅全部 CRTAM 一抗
  • 描述
    小鼠多克隆抗体to CRTAM
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human CRTAM (AAH70266.1, 393 aa).

  • 阳性对照
    • CRTAM transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 60, 75 kDa (predicted molecular weight: 45 kDa).

靶标

  • 功能Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
  • 组织特异性In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues.
  • 序列相似性Belongs to the nectin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD355 antibody
    • Class I MHC restricted T cell associated molecule antibody
    • Class-I MHC-restricted T-cell-associated molecule antibody
    • CRTAM antibody
    • CRTAM_HUMAN antibody
    • Cytotoxic and regulatory T cell molecule antibody
    • Cytotoxic and regulatory T-cell molecule antibody
    see all

Anti-CRTAM antibody 图像

  • All lanes : Anti-CRTAM antibody (ab69690) at 1/500 dilution

    Lane 1 : CRTAM transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 45 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

Anti-CRTAM antibody (ab69690)参考文献

ab69690 has not yet been referenced specifically in any publications.

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