概述

  • 产品名称
  • 描述
    兔多克隆抗体to CROP
  • 经测试应用
    适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 200 and 250 of human CROP (NP_057508.2).

  • 阳性对照
    • Whole cell lysate from HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab80415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
  • 应用说明
    IP: Use at 2 - 5 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.
    • 组织特异性
      Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.
    • 序列相似性
      Belongs to the Luc7 family.
    • 翻译后修饰
      Phosphorylated in vitro by SRPK1, SRPK2 and CLK1.
    • 细胞定位
      Nucleus speckle. The subnuclear localization is affected by cisplatin.
    • Information by UniProt
    • 数据库链接
    • 别名
      • cAMP regulatory element-associated protein 1 antibody
      • Cisplatin resistance-associated overexpressed protein antibody
      • Cisplatin resistance-associated-overexpressed protein antibody
      • CRA antibody
      • CRE-associated protein 1 antibody
      • CREAP-1 antibody
      • CREAP1 antibody
      • CROP antibody
      • hLuc7A antibody
      • LC7L3_HUMAN antibody
      • LUC7 like 3 pre mRNA splicing factor antibody
      • Luc7-like protein 3 antibody
      • Luc7A antibody
      • LUC7L3 antibody
      • O48 antibody
      • OA48 18 antibody
      • Okadaic acid-inducible phosphoprotein OA48-18 antibody
      see all

    图片

    • Detection of human CROP in Immunoprecipitates of whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab80415 at 3 µg/mg lysate for IP (lane 1). Lane 2 represents control IgG IP. Subsequent WB detection used ab80412 (which recognizes an upstream epitope) at 1 µg/ml.

    文献

    ab80415 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab80415.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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