概述

  • 产品名称Anti-CRMP4抗体
    参阅全部 CRMP4 一抗
  • 描述
    小鼠单克隆抗体to CRMP4
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD EGVRSASKR, corresponding to amino acids 457-556 of Human CRMP4

性能

应用

Our Abpromise guarantee covers the use of ab54819 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa.
IHC-P Use a concentration of 3 µg/ml.

靶标

  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • 组织特异性Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 翻译后修饰Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
  • 细胞定位Cytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Collapsin response mediator protein 4 antibody
    • Collapsin response mediator protein 4 long antibody
    • CRMP 4 antibody
    • CRMP-4 antibody
    • CRMP4 antibody
    • Dihydropyrimidinase like 3 antibody
    • Dihydropyrimidinase related protein 3 antibody
    • Dihydropyrimidinase-related protein 3 antibody
    • DPYL3_HUMAN antibody
    • DPYSL3 antibody
    • DRP 3 antibody
    • DRP-3 antibody
    • DRP3 antibody
    • LCRMP antibody
    • TUC4 antibody
    • ULIP 1 antibody
    • ULIP antibody
    • ULIP-1 antibody
    • ULIP1 antibody
    • UNc 33 like phosphoprotein 1 antibody
    • Unc 33 like phosphoprotein antibody
    • Unc-33-like phosphoprotein 1 antibody
    see all

Anti-CRMP4 antibody 图像



  • Predicted band size : 62 kDa
    CRMP4 antibody (ab54819) at 1ug/lane + Jurkat cell lysate at 25ug/lane.
  • ab54819 at 3 ug/ml staining CRMP4 in human Ovary tissue sections by Immunohistochemistry (Formallin /PFA-fixed paraffin embedded tissue sections)

Anti-CRMP4 antibody (ab54819)参考文献

ab54819 has not yet been referenced specifically in any publications.

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