Recombinant fragment, corresponding to amino acids 422 - 567 of Human CRMP4 (NM_001387).
- WB: Human fetal brain lysate
IHC-P: Human fetal skeletal muscle
Lyophilised:Add 200 ul sterile distilled water.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/1000 - 1/2000. Detects a band of approximately 61 kDa (predicted molecular weight: 62 kDa).
||1/100 - 1/500.
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Cytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Information by UniProt
- Collapsin response mediator protein 4 antibody
- Collapsin response mediator protein 4 long antibody
- CRMP 4 antibody
Anti-CRMP4 antibody 图像
Western blot - CRMP4 antibody (ab101009)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CRMP4 antibody (ab101009)
ab101009, at a 1/100 dilution, staining CRMP4 in formalin fixed, paraffin embedded Human fetal skeletal muscle. The image shows cytoplasmic staining of the antibody.
Anti-CRMP4 antibody (ab101009)参考文献
This product has been referenced in:
- Chen SL et al. Targeting CRMP-4 by lentivirus-mediated RNA interference inhibits SW480 cell proliferation and colorectal cancer growth. Exp Ther Med 12:2003-2008 (2016).
Read more (PubMed: 27698685) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"