Anti-CRMP3抗体- ChIP Grade (ab36217)


  • 产品名称Anti-CRMP3抗体- ChIP Grade
    参阅全部 CRMP3 一抗
  • 描述
    兔多克隆抗体to CRMP3 - ChIP Grade
  • 特异性No cross reactivity was detected with CRMP1, CRMP2, CRMP4 or CRMP5.
  • 经测试应用适用于: WB, ChIP, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 15 residue synthetic peptide derived from C-terminal domain of human CRMP3.



Our Abpromise guarantee covers the use of ab36217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 65 kDa.
ChIP Use at an assay dependent concentration. PubMed: 23443259
IHC-Fr 1/500.
IHC-P Use at an assay dependent concentration.


  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Collapsin response mediator protein 3 antibody
    • CRMP 3 antibody
    • CRMP-3 antibody
    • CRMP3 antibody
    • Dihydropyrimidinase like 4 antibody
    • Dihydropyrimidinase related protein 4 antibody
    • Dihydropyrimidinase-related protein 4 antibody
    • DPYL4_HUMAN antibody
    • DPYSL4 antibody
    • DRP 4 antibody
    • DRP-4 antibody
    • DRP4 antibody
    • ULIP 4 antibody
    • ULIP-4 antibody
    • ULIP4 antibody
    • UNC33 like phosphoprotein 4 antibody
    • UNC33-like phosphoprotein 4 antibody
    see all

Anti-CRMP3 antibody - ChIP Grade 图像

  • All lanes : Anti-CRMP3 antibody - ChIP Grade (ab36217)

    Lane 1 : E.coli transformed with cDNA of human CRMP1
    Lane 2 : E.coli transformed with cDNA of human CRMP2
    Lane 3 : E.coli transformed with cDNA of human CRMP3
    Lane 4 : E.coli transformed with cDNA of human CRMP4
    Lane 5 : E.coli transformed with cDNA of human CRMP5

    Predicted band size : 65 kDa
    Observed band size : 65 kDa
  • IHC image of ab36217 staining in human hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab36217, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-CRMP3 antibody - ChIP Grade (ab36217)参考文献

This product has been referenced in:
  • Hou ST  et al. Collapsin response mediator protein 3 deacetylates histone H4 to mediate nuclear condensation and neuronal death. Sci Rep 3:1350 (2013). ChIP ; Mouse . Read more (PubMed: 23443259) »

See 1 Publication for this product

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