概述

  • 产品名称Anti-CRMP2抗体
    参阅全部 CRMP2 一抗
  • 描述
    兔多克隆抗体to CRMP2
  • 特异性No cross reactivity was detected with CRMP1, CRMP3, CRMP4 or CRMP5.
  • 经测试应用适用于: WB, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator.

性能

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应用

Our Abpromise guarantee covers the use of ab36201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 63 kDa.Can be blocked with CRMP2 peptide (ab196858).
IHC-Fr 1/500.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 翻译后修饰3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Collapsin response mediator protein 2 antibody
    • Collapsin response mediator protein antibody
    • Collapsin response mediator protein hCRMP 2 antibody
    • CRAM antibody
    • CRMP 2 antibody
    • CRMP-2 antibody
    • CRMP2 antibody
    • DHPRP 2 antibody
    • DHPRP2 antibody
    • Dihydropyrimidinase 2 antibody
    • Dihydropyrimidinase like 2 antibody
    • Dihydropyrimidinase like 2 long form antibody
    • Dihydropyrimidinase related protein 2 antibody
    • Dihydropyrimidinase-related protein 2 antibody
    • DPYL 2 antibody
    • DPYL2 antibody
    • DPYL2_HUMAN antibody
    • DPYSL 2 antibody
    • Dpysl2 antibody
    • DRP-2 antibody
    • DRP2 antibody
    • Musunc 33 antibody
    • Musunc33 antibody
    • N2A3 antibody
    • TOAD 64 antibody
    • TOAD64 antibody
    • ULIP 2 protein antibody
    • ULIP-2 antibody
    • Ulip2 antibody
    • Unc-33-like phosphoprotein 2 antibody
    see all

Anti-CRMP2 antibody 图像

  • All lanes : Anti-CRMP2 antibody (ab36201)

    Lane 1 : E.coli transformed with cDNA of human CRMP1
    Lane 2 : E.coli transformed with cDNA of human CRMP2
    Lane 3 : E.coli transformed with cDNA of human CRMP3
    Lane 4 : E.coli transformed with cDNA of human CRMP4
    Lane 5 : E.coli transformed with cDNA of human CRMP5


    Predicted band size : 63 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)
  • Ab36201 staining human CRMP2 in olfactory receptor neurons within the olfactory mucosa by immunohistochemistry.

Anti-CRMP2 antibody (ab36201)参考文献

This product has been referenced in:
  • Samara A  et al. Proteomics reveal rat hippocampal lateral asymmetry. Hippocampus 21:108-19 (2011). WB ; Rat . Read more (PubMed: 20020437) »
  • Gelman BB & Nguyen TP Synaptic proteins linked to HIV-1 infection and immunoproteasome induction: proteomic analysis of human synaptosomes. J Neuroimmune Pharmacol 5:92-102 (2010). WB ; Human . Read more (PubMed: 19693676) »

See all 2 Publications for this product

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Yes, both detection methods should be suitable for this antibody.

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