概述

  • 产品名称Anti-CRMP1抗体
    参阅全部 CRMP1 一抗
  • 描述
    兔多克隆抗体to CRMP1
  • 特异性ab83944 is expected to recognize only the longest isoform of CRMP1.
  • 经测试应用适用于: ICC/IF, WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    18 amino acid peptide from near the amino terminus of Human CRMP1 (AAH07613).

  • 阳性对照
    • Rat Brain Tissue Lysate; mouse brain tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab83944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 74 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 2.5 µg/ml.

靶标

  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
  • 组织特异性Brain.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes and the mitotic spindle during metaphase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Collapsin response mediator protein 1 antibody
    • CRMP 1 antibody
    • CRMP-1 antibody
    • Crmp1 antibody
    • Dihydropyrimidinase like 1 antibody
    • Dihydropyrimidinase related protein 1 antibody
    • Dihydropyrimidinase-related protein 1 antibody
    • DPYL1_HUMAN antibody
    • DPYSL1 antibody
    • DRP 1 antibody
    • DRP-1 antibody
    • DRP1 antibody
    • ULIP-3 antibody
    • Ulip3 antibody
    • Unc-33-like phosphoprotein 3 antibody
    see all

Anti-CRMP1 antibody 图像

  • Immunofluorescence of CRMP1 in mouse brain tissue with ab83944 at 5 ug/mL.

  • Immunohistochemistry of mouse brain tissue with ab83944 at 2.5 μg/mL.

  • Lane 1 : Anti-CRMP1 antibody (ab83944) at 1 µg/ml
    Lane 2 : Anti-CRMP1 antibody (ab83944) at 2 µg/ml

    Lane 1 : rat brain tissue lysate
    Lane 2 : rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 74 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

Anti-CRMP1 antibody (ab83944)参考文献

This product has been referenced in:
  • Moreira JM  et al. Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. Mol Oncol 4:539-61 (2010). IHC-P ; Human . Read more (PubMed: 21036680) »

See 1 Publication for this product

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