概述

  • 产品名称Anti-CRMP1抗体
    参阅全部 CRMP1 一抗
  • 描述
    兔多克隆抗体to CRMP1
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 16 amino acid peptide from near the centre of human CRMP1.

  • 阳性对照
    • Caco-2 cell lysate. Human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab62560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
  • 组织特异性Brain.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes and the mitotic spindle during metaphase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Collapsin response mediator protein 1 antibody
    • CRMP 1 antibody
    • CRMP-1 antibody
    • Crmp1 antibody
    • Dihydropyrimidinase like 1 antibody
    • Dihydropyrimidinase related protein 1 antibody
    • Dihydropyrimidinase-related protein 1 antibody
    • DPYL1_HUMAN antibody
    • DPYSL1 antibody
    • DRP 1 antibody
    • DRP-1 antibody
    • DRP1 antibody
    • ULIP-3 antibody
    • Ulip3 antibody
    • Unc-33-like phosphoprotein 3 antibody
    see all

Anti-CRMP1 antibody 图像

  • Lane 1 : Anti-CRMP1 antibody (ab62560) at 1 µg/ml
    Lane 2 : Anti-CRMP1 antibody (ab62560) at 2 µg/ml
    Lane 3 : Anti-CRMP1 antibody (ab62560) at 4 µg/ml

    Lane 1 : Caco-2 cell lysate
    Lane 2 : Caco-2 cell lysate
    Lane 3 : Caco-2 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 62 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 62 kDa,68 kDa. We are unsure as to the identity of these extra bands.
  • Immunofluorescence of CRMP1 in Human Brain cells using ab62560 at 20 ug/ml.

  • ab62560, at 10µg/ml, staining CRMP1 in human brain tissue by immunohistochemistry using paraffin-embedded tissue.

Anti-CRMP1 antibody (ab62560)参考文献

This product has been referenced in:
  • Braunschweig D  et al. Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Transl Psychiatry 3:e277 (2013). Read more (PubMed: 23838888) »

See 1 Publication for this product

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