Mouse, Rat, Human
A 15 amino acid peptide from near the carboxy terminus of human CRMP1
3T3 cell lysate. Human brain tissue.
Shipped at 4°C. Store at +4°C.
Preservative: 0.02% Sodium Azide
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).
Use a concentration of 2 µg/ml.
Use at an assay dependent concentration. PubMed: 20489728
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes and the mitotic spindle during metaphase.
Information by UniProt
Collapsin response mediator protein 1 antibody
CRMP 1 antibody
Western blot - Anti-CRMP1 antibody (ab62558)
Lane 1 :
Anti-CRMP1 antibody (ab62558) at 0.5 µg/ml
Lane 2 :
Anti-CRMP1 antibody (ab62558) at 1 µg/ml
Lane 3 :
Anti-CRMP1 antibody (ab62558) at 2 µg/ml
All lanes :
3T3 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size:
Observed band size:
70 kDa (
why is the actual band size different from the predicted?
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP1 antibody (ab62558)
ab62558, at 2µg/ml, staining CRMP1 in human brain by immunohistochemistry using paraffin-embedded tissue.
Immunocytochemistry/ Immunofluorescence - Anti-CRMP1 antibody (ab62558)
Immunofluorescence of CRMP1 in Human Brain cells using ab62558 at 10 ug/ml.
This product has been referenced in:
et al. Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway. Cancer Res 77:2018-2028 (2017).
Read more (PubMed: 28202526) »
et al. Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons. Cell Death Differ : (2010).
Read more (PubMed: 20489728) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"