概述

  • 产品名称Anti-CRLF2抗体
    参阅全部 CRLF2 一抗
  • 描述
    小鼠单克隆抗体to CRLF2
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 23-133 of Human CRLF2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 42 kDa.
ICC/IF Use a concentration of 5 µg/ml.

靶标

  • 功能Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
  • 组织特异性Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    Contains 1 fibronectin type-III domain.
  • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is important for association with JAKs.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CRL 2 antibody
    • CRL2 antibody
    • CRLF 2 antibody
    • Crlf2 antibody
    • CRLF2_HUMAN antibody
    • CRLF2Y antibody
    • Cytokine receptor CRL2 precusor antibody
    • Cytokine receptor like 2 antibody
    • Cytokine receptor like factor 2 antibody
    • Cytokine receptor like factor 2 precursor antibody
    • Cytokine receptor-like 2 antibody
    • Cytokine receptor-like factor 2 antibody
    • IL XR antibody
    • IL-XR antibody
    • ILXR antibody
    • Thymic stromal derived lymphopoietin receptor antibody
    • Thymic stromal lymphopoietin protein receptor antibody
    • Thymic stromal lymphopoietin receptor antibody
    • TSLP receptor antibody
    • TSLPR antibody
    see all

Anti-CRLF2 antibody 图像



  • Predicted band size : 42 kDa
    CRLF2 antibody (ab56373) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ICC/IF image of ab56373 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab56373, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96879, DyLight® 488 goat anti-mouse IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CRLF2 antibody (ab56373)参考文献

ab56373 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab56373.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"