概述

  • 产品名称
  • 描述
    小鼠单克隆抗体to CRLF1
  • 经测试应用
    适用于: WB, ELISA, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: PEKPVNISCW SKNMKDLTCR WTPGAHGETF LHTNYSLKYK LRWYGQDNTC EEYHTVGPHS CHIPKDLALF TPYEIWVEAT NRLGSARSDV LTLDIL, corresponding to amino acids 135-231 of Human CRLF1

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 同种型
    IgG2a
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56500 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 46 kDa.
ELISA Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

靶标

  • 相关性
    CRLF1 (Cytokine receptor-like factor 1) is a cytokine receptor subunit. It forms a heteromeric complex with cardiotrophin-like cytokine (CLC) and the CRLF1/CLC complex is a ligand for the ciliary neurotrophic factor receptor (CNTFR). Mutations in CRLF1 are responsible for both Crisponi and cold-induced sweating syndromes.
  • 细胞定位
    Secreted
  • 数据库链接
  • 别名
    • CISS 1 antibody
    • CISS antibody
    • CISS1 antibody
    • class I cytokine receptor antibody
    • CLF 1 antibody
    • CLF antibody
    • CLF1 antibody
    • CRLF 1 antibody
    • Cytokine like factor 1 antibody
    • Cytokine receptor like factor 1 antibody
    • cytokine type 1 receptor CRLP 1 antibody
    • NR 6 antibody
    • NR6 antibody
    • ZcytoR 5 antibody
    • ZcytoR5 antibody
    see all

图片



  • Predicted band size : 46 kDa
  • Immunoprecipitation of CRLF1 transfected lysate using ab56500. The predicted band size of 46kDa.
  • All lanes : Anti-CRLF1 antibody (ab56500)

    Lane 1 : CRLF1 transfected lysate (293T cell line)
    Lane 2 : Non-transfected lysate


    Predicted band size : 46 kDa

文献

This product has been referenced in:
  • Herholz J  et al. Differential secretion of the mutated protein is a major component affecting phenotypic severity in CRLF1-associated disorders. Eur J Hum Genet 19:525-33 (2011). Read more (PubMed: 21326283) »

See 1 Publication for this product

客户评价及客户问答

Thank you for providing that information. I now understand more fully how the antibody has been used.

I think what may be contributing to the problems in achieving the results expected is the level of protein present in your sample. I would s...

Read More

Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

If ...

Read More

Thank you for contacting us.


The clone number is XXXXX.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册