重组
RabMAb

Anti-Cripto1抗体[EPNCIR106A] (ab108391)

概述

  • 产品名称Anti-Cripto1抗体[EPNCIR106A]
    参阅全部 Cripto1 一抗
  • 描述
    兔单克隆抗体[EPNCIR106A] to Cripto1
  • 经测试应用适用于: WB, IP, ICC, Flow Cytmore details
    不适用于: IHC-P
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Cripto 1.

  • 阳性对照
    • NCCIT cell lysate
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of David Solomon.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Alternative versions available:

    Anti-Cripto1 antibody (HRP) [EPNCIR106A] (ab203468)

    Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5, 675, 063 and/or 7, 429, 487.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

性能

应用

Our Abpromise guarantee covers the use of ab108391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
IP 1/10 - 1/100.
ICC 1/100 - 1/250.
Flow Cyt Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IHC-P.
  • 靶标

    • 功能Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
    • 组织特异性Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
    • 序列相似性Contains 1 EGF-like domain.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CR antibody
      • CRGF antibody
      • Cripto 1 antibody
      • Cripto 1 growth factor antibody
      • cripto antibody
      • Cripto-1 growth factor antibody
      • Cripto1 growth factor antibody
      • Epidermal growth factor like cripto protein CR1 antibody
      • Epidermal growth factor-like cripto protein CR1 antibody
      • TDGF 1 antibody
      • TDGF1 antibody
      • TDGF1_HUMAN antibody
      • Teratocarcinoma derived growth factor 1 antibody
      • Teratocarcinoma-derived growth factor 1 antibody
      see all

    Anti-Cripto1 antibody [EPNCIR106A] 图像

    • Flow Cytometry analysis of NCCIT(human pluripotent embryonal carcinoma) cells labeling Cripto1 with purified ab108391 
      at 1/2200 dilution (1ug/ml) (red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. A Goat anti rabbit IgG (Alexa Fluor® 488)(1/2000 dilution) was used as the secondary antibody. Rabbit monoclonal IgG (Black) was used as the isotype control, cells without incubation with primary antibody and secondary antibody (Blue) were used as the unlabeled control.

    • Anti-Cripto1 antibody [EPNCIR106A] (ab108391) at 1/1000 dilution + NCCIT cell lysate at 10 µg

      Predicted band size : 21 kDa
      Observed band size : 21 kDa

    Anti-Cripto1 antibody [EPNCIR106A] (ab108391)参考文献

    ab108391 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"