概述

  • 产品名称
  • 描述
    兔多克隆抗体to CRF1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish, African green monkey
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 292-341 (RPGVYTDYIY QGPMILVLLI NFIFLFNIVR ILMTKLRAST TSETIQYRKA) of Human CRF1 (NP_001138620).

  • 阳性对照
    • HeLa cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab125509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
  • 组织特异性
    Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
  • 序列相似性
    Belongs to the G-protein coupled receptor 2 family.
  • 翻译后修饰
    C-terminal Ser or Thr residues may be phosphorylated.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Corticotropin releasing factor type 1 receptor antibody
    • corticotropin releasing hormone receptor 1 antibody
    • Corticotropin-releasing factor receptor 1 antibody
    • Corticotropin-releasing hormone receptor 1 antibody
    • CRF R antibody
    • crf receptor 1 antibody
    • crf receptor type 1 antibody
    • crf type 1 antibody
    • CRF-R antibody
    • CRF-R-1 antibody
    • CRF-R1 antibody
    • CRF1 antibody
    • CRFR antibody
    • CRFR-1 antibody
    • CRFR1 antibody
    • CRFR1_HUMAN antibody
    • CRH-R-1 antibody
    • CRH-R1 antibody
    • CRH-R1h antibody
    • CRHR antibody
    • Crhr1 antibody
    • CRHR1f antibody
    • CRHR1L antibody
    see all

Anti-CRF1 antibody 图像

  • Anti-CRF1 antibody (ab125509) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 51 kDa

实验方案

Anti-CRF1 antibody (ab125509)参考文献

ab125509 has not yet been referenced specifically in any publications.

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