N-terminal extracellular domain of Human protein.
Synthetic peptide, conjugated to KLH, derived from N-terminal extracellular domain of Human CRF1
Human Pars Intermedia tissue
Shipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide
Constituent: 99% PBS
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
Belongs to the G-protein coupled receptor 2 family.
C-terminal Ser or Thr residues may be phosphorylated.
Information by UniProt
Corticotropin releasing factor type 1 receptor antibody
corticotropin releasing hormone receptor 1 antibody
Corticotropin-releasing factor receptor 1 antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRF1 antibody (ab115286)
Human Pars Intermedia formalin-fixed, paraffin-embedded tissue stained with ab115286 at 20 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
has not yet been referenced specifically in any publications.
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