概述

  • 产品名称Anti-CRCP抗体
    参阅全部 CRCP 一抗
  • 描述
    兔多克隆抗体to CRCP
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow
  • 免疫原

    antigen sequence: TPCRHQSPEI VREFLTALKS HKLTKAEKLQ LLNHRPVTAV EIQLMVEESE ERLTEEQIEA LLHTVTSILP AEPEAEQKKN TNSNVAMDEE DPA, corresponding to amino acids 56-148 of Human CRCP.

  • 阳性对照
    • Human testis tissue; RT-4 and U-251 MG cell lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab121255 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform Heat Induced Epitope Retrieval (HIER) at pH 6.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.
    Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
  • 组织特异性Ubiquitous. Most prevalent in testis.
  • 序列相似性Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
  • 细胞定位Nucleus. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Calcitonin gene related peptide receptor component antibody
    • Calcitonin gene related peptide receptor component protein antibody
    • Calcitonin gene-related peptide-receptor component protein antibody
    • CGRP receptor component protein antibody
    • CGRP-RCP antibody
    • CGRP-receptor component protein antibody
    • CGRPRCP antibody
    • CRCP antibody
    • DNA-directed RNA polymerase III subunit RPC9 antibody
    • HsC17 antibody
    • RCP antibody
    • RCP9 antibody
    • RNA polymerase III subunit C9 antibody
    • RPC9_HUMAN antibody
    see all

Anti-CRCP antibody 图像

  • Immunofluorescent staining of human cell line A-431 shows positivity in nucleus.
  • ab121255, at 1/30 dilution, staining CRCP in paraffin-embedded Human testis by Immunohistochemistry showing cytoplasmic and nuclear positivity of cells in seminiferus ducts.

Anti-CRCP antibody (ab121255)参考文献

ab121255 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121255.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"