概述

  • 产品名称
  • 描述
    兔多克隆抗体to CPSF2
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Chimpanzee, Rhesus monkey, Gorilla, Xenopus tropicalis
  • 免疫原

    corresponding to a region within internal sequence amino acids 450-500 of Human CPSF2 (NP_059133.1)

  • 阳性对照
    • Human Anaplastic Thyroid Carcinoma, Human Breast Carcinoma, Human Linitis Plastica Stomach Cancer, Human Ovarian Carcinoma, Human Testicular Seminoma.

性能

应用

Our Abpromise guarantee covers the use of ab100807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure with citrate buffer will enhance staining.

靶标

  • 相关性
    CPSF2 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily. It is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3 prime-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. A poly(A) tail is added to eukaryotic mRNA precursors after tightly coupled cleavage and polyadenylation reactions at their 3-prime ends.
  • 细胞定位
    Nuclear
  • 数据库链接
  • 别名
    • Cleavage and polyadenylation specific factor 2 antibody
    • cleavage and polyadenylation specific factor 2, 100kDa antibody
    • Cleavage and polyadenylation specificity factor 100 kDa subunit antibody
    • Cleavage and polyadenylation specificity factor subunit 2 antibody
    • CPSF 100 kDa subunit antibody
    • CPSF 2 antibody
    • CPSF100 antibody
    • KIAA1367 antibody
    • zgc:92484 antibody
    see all

图片

  • ab100807, at 1/250 dilution, staining CPSF2 in Human ovarian carcinoma by immunohistochemistry.
  • ab100807, at 1/250 dilution, staining CPSF2 in Mouse teratoma by immunohistochemistry.

文献

ab100807 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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