概述

  • 产品名称
  • 描述
    兔多克隆抗体to CP2c
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Xenopus laevis, Pufferfish
  • 免疫原

    Synthetic peptide: GAYSMSDVLA LPIFKQEESS LPPDNENKIL PFQYVLCAAT SPAVKLHDET , corresponding to N terminal amino acids 37-86 of Human CP2c

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab80445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
  • 组织特异性
    Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level).
  • 序列相似性
    Belongs to the grh/CP2 family. CP2 subfamily.
  • 发展阶段
    Expressed in fetal erythroid tissue.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha globin transcription factor CP2 antibody
    • Alpha-globin transcription factor CP2 antibody
    • CP2 antibody
    • Late SV40 factor antibody
    • LBP 1C antibody
    • LBP1C antibody
    • LSF antibody
    • LSF1D antibody
    • SAA3 enhancer factor antibody
    • SEF antibody
    • TFCP2 antibody
    • TFCP2_HUMAN antibody
    • TFCP2C antibody
    • Transcription factor CP2 antibody
    • Transcription factor LSF antibody
    see all

图片

  • Anti-CP2c antibody (ab80445) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 57 kDa

实验方案

文献

This product has been referenced in:
  • Teperek M  et al. Sperm and spermatids contain different proteins and bind distinct egg factors. Int J Mol Sci 15:16719-40 (2014). WB ; Frog . Read more (PubMed: 25244019) »

See 1 Publication for this product

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