Anti-Cox-3抗体(ab37269)
Key features and details
- Rabbit polyclonal to Cox-3
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Cox-3抗体 -
描述
兔多克隆抗体to Cox-3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to residues from the N-terminus of Cox-3 (Mouse).
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阳性对照
- mouse small intestinal tissue
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 3687 Cox-3 Antibody. 3687-100 is the same size as the 100 µg size of ab37269.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 1% BSA, 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab37269于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 69 kDa.
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说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 69 kDa. |
靶标
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相关性
COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (nonsteroidal anti-inflammatory drugs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis. In rodents and humans, COX-3 encodes proteins with completely different amino acid sequences from COX-1 or COX-2, and without COX activity. COX-3 is thought to be a splice variant of COX-1 which retains intron one. It has been suggested that COX-3 may be the key to unlocking the mechanism of action of acetaminophen. -
细胞定位
Membrane-associated; Microsomal membrane. -
数据库链接
- Entrez Gene: 19224 Mouse
- SwissProt: P22437 Mouse
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别名
- Cox3 antibody
- Cyclooxygenase 1 antibody
- Ptgs1 antibody
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab37269 被引用在 1 文献中.
- Cui TZ et al. Modulation of the respiratory supercomplexes in yeast: enhanced formation of cytochrome oxidase increases the stability and abundance of respiratory supercomplexes. J Biol Chem 289:6133-41 (2014). WB ; Saccharomyces cerevisiae . PubMed: 24421313