Anti-Cortisol抗体[CORT-2] (ab1952)

概述

  • 产品名称Anti-Cortisol抗体[CORT-2]
    参阅全部 Cortisol 一抗
  • 描述
    小鼠单克隆抗体[CORT-2] to Cortisol
  • 特异性Cortisol-BSA conjugate and free cortisol. There is no cross-reactivity with BSA. CORT-2 does not bind with cortisone.
  • 经测试应用适用于: competitive binding assaysmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human) conjugated to BSA.

  • 常规说明Concentration varies from lot to lot and can be provided on request.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明Purity tested by elcetrophoresis.
  • 克隆单克隆
  • 克隆编号CORT-2
  • 骨髓瘤Sp2/0
  • 同种型IgG3
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab1952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
competitive binding assays Use at an assay dependent dilution.

靶标

  • 相关性Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
  • 细胞定位Secreted

Anti-Cortisol antibody [CORT-2] 图像

  • Cross-reactivity, % 50% displacement of cortisol-3-125-Iodine.

Anti-Cortisol antibody [CORT-2] (ab1952)参考文献

ab1952 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

To be honest we do not have an antibody that we have tested with this kind of novel assay, and therefore do not know if it would work nor can we guarantee it.

Although ab1949 may work, I may recommend ab...

Read More

Cross-reaction of cortisol antibodies with cortisone is the following: ab1949 - 0.6 %, ab1951 - 35 % and ab1952 - 0 %.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"