产品名称 Anti-Cortactin抗体 参阅全部 Cortactin 一抗
WB, ELISA more details
A synthesized non-phosphopeptide derived from human Cortactin around the phosphorylation site of tyrosine 421 (P-I-Y
存放说明 Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
纯度 Immunogen affinity purified
Corresponding phospho antibody
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 62 kDa).
功能 Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
序列相似性 Contains 7 cortactin repeats. Contains 1 SH3 domain.
结构域 The SH3 motif may mediate binding to the cytoskeleton.
翻译后修饰 Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
细胞定位 Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle. Associated with membrane ruffles and lamellipodia.
Information by UniProt
EMS 1 antibody
Anti-Cortactin antibody 图像
Western blot - Cortactin antibody (ab47582)
All lanes : Anti-Cortactin antibody (ab47582) at 1/500 dilution Lane 1 : Extracts from Hela cells treated with hydrogen peroxide. Lane 2 : Extracts from Hela cells treated with hydrogen peroxide and immunogenic peptide. Lysates/proteins at 30 µg per lane. Predicted band size : 62 kDa Observed band size : 85 kDa ( why is the actual band size different from the predicted?)
Anti-Cortactin antibody (ab47582)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"