产品名称 Anti-Cortactin抗体 参阅全部 Cortactin 一抗
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Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 272-302 of Human Cortactin (NP_005222.2)
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium azide Constituent: 99% PBS
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纯度 Immunogen affinity purified
纯化说明 ab116554 was purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 62 kDa.
功能 Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
序列相似性 Contains 7 cortactin repeats. Contains 1 SH3 domain.
结构域 The SH3 motif may mediate binding to the cytoskeleton.
翻译后修饰 Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
细胞定位 Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle. Associated with membrane ruffles and lamellipodia.
Information by UniProt
EMS 1 antibody
Anti-Cortactin antibody 图像
Anti-Cortactin antibody (ab116554)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"