概述

  • 产品名称Anti-Cortactin抗体
    参阅全部 Cortactin 一抗
  • 描述
    兔多克隆抗体to Cortactin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 272-302 of Human Cortactin (NP_005222.2)

  • 阳性对照
    • HeLa cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab116554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 62 kDa.

靶标

  • 功能Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
  • 序列相似性Contains 7 cortactin repeats.
    Contains 1 SH3 domain.
  • 结构域The SH3 motif may mediate binding to the cytoskeleton.
  • 翻译后修饰Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
  • 细胞定位Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle. Associated with membrane ruffles and lamellipodia.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amplaxin antibody
    • CTTN antibody
    • EMS 1 antibody
    • EMS1 antibody
    • FLJ34459 antibody
    • Mammary tumor and squamous cell carcinoma associated antibody
    • Oncogene EMS1 antibody
    • p80/85 src substrate antibody
    • Src substrate cortactin antibody
    • SRC8_HUMAN antibody
    see all

Anti-Cortactin antibody 图像

  • Anti-Cortactin antibody (ab116554) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 62 kDa

Anti-Cortactin antibody (ab116554)参考文献

ab116554 has not yet been referenced specifically in any publications.

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