概述

  • 产品名称Anti-Coronin 1a抗体
    参阅全部 Coronin 1a 一抗
  • 描述
    兔多克隆抗体to Coronin 1a
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 250 and 300 of Human Coronin 1a (NP_009005.1)

  • 阳性对照
    • human stomach adenocarcinoma, mouse fibroma.

性能

应用

Our Abpromise guarantee covers the use of ab84504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
    • 组织特异性Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
    • 序列相似性Belongs to the WD repeat coronin family.
      Contains 7 WD repeats.
    • 细胞定位Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle > phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Actin binding protein antibody
      • CLABP antibody
      • Clipin A antibody
      • Clipin-A antibody
      • CLIPINA antibody
      • COR1A_HUMAN antibody
      • CORO1A antibody
      • Coronin 1 antibody
      • Coronin actin binding protein 1A antibody
      • Coronin like protein A antibody
      • Coronin like protein p57 antibody
      • Coronin-1A antibody
      • Coronin-like protein A antibody
      • Coronin-like protein p57 antibody
      • FLJ41407 antibody
      • HCORO1 antibody
      • MGC117380 antibody
      • OTTHUMP00000163017 antibody
      • p57 antibody
      • TACO antibody
      • Tryptophan aspartate containing coat protein antibody
      • Tryptophan aspartate-containing coat protein antibody
      see all

    Anti-Coronin 1a antibody 图像

    • Detection of Human Coronin 1a by Immunohistochemistry on formalin fixed paraffin embedded section of Human stomach adenocarcinoma using 1/250 ab84504. Detection: DAB staining
    • Detection of mouse Coronin 1a by Immunohistochemistry on formalin fixed paraffin embedded section of Mouse fibroma using 1/250 ab84504. Detection: DAB staining

    Anti-Coronin 1a antibody (ab84504)参考文献

    ab84504 has not yet been referenced specifically in any publications.

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