概述

  • 产品名称Anti-Coronin 1a抗体
    参阅全部 Coronin 1a 一抗
  • 描述
    鸡多克隆抗体to Coronin 1a
  • 经测试应用适用于: ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Cultured adult mouse brain cells.

性能

应用

Our Abpromise guarantee covers the use of ab53395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/1000.

靶标

  • 功能May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
  • 组织特异性Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
  • 序列相似性Belongs to the WD repeat coronin family.
    Contains 7 WD repeats.
  • 细胞定位Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle > phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Actin binding protein antibody
    • CLABP antibody
    • Clipin A antibody
    • Clipin-A antibody
    • CLIPINA antibody
    • COR1A_HUMAN antibody
    • CORO1A antibody
    • Coronin 1 antibody
    • Coronin actin binding protein 1A antibody
    • Coronin like protein A antibody
    • Coronin like protein p57 antibody
    • Coronin-1A antibody
    • Coronin-like protein A antibody
    • Coronin-like protein p57 antibody
    • FLJ41407 antibody
    • HCORO1 antibody
    • MGC117380 antibody
    • OTTHUMP00000163017 antibody
    • p57 antibody
    • TACO antibody
    • Tryptophan aspartate containing coat protein antibody
    • Tryptophan aspartate-containing coat protein antibody
    see all

Anti-Coronin 1a antibody 图像

  • Ab53395 at 1/1000 dilution staining cultured adult mouse brain cells.

Anti-Coronin 1a antibody (ab53395)参考文献

This product has been referenced in:
  • Suo D  et al. Coronin-1 and calcium signaling governs sympathetic final target innervation. J Neurosci 35:3893-902 (2015). Read more (PubMed: 25740518) »
  • Suo D  et al. Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival. Nat Neurosci 17:36-45 (2014). ICC/IF ; Rat . Read more (PubMed: 24270184) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab53395.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"