The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
1/250 - 1/500.
功能May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi.
序列相似性Belongs to the WD repeat coronin family. Contains 8 WD repeats.
翻译后修饰The membrane-associated form is phosphorylated on tyrosine residues.
细胞定位Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle. Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.