Mouse, Rat, Rabbit, Cow, Zebrafish
Recombinant fragment, corresponding to a region within amino acids 1-183 of Human CORO1B (NP_065174).
- H1299, A431, 293T, MOLT4 or Raji cell lines.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/3000. Predicted molecular weight: 54 kDa.
||1/100 - 1/500.
Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
Belongs to the WD repeat coronin family.
Contains 5 WD repeats.
Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
Cytoplasm > cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
Information by UniProt
- COR1B_HUMAN antibody
- CORO 1B antibody
- CORO1B antibody
Western blot - CORO1B antibody (ab97650)
Anti-CORO1B antibody (ab97650) at 1/1000 dilution + A431 whole cell lysate at 30 µg
Predicted band size : 54 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CORO1B antibody (ab97650)
ab97650 at 1/500 dilution staining CORO1B in paraffin-embedded H1299 xenograft by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
has not yet been referenced specifically in any publications.
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