概述

  • 产品名称Anti-CORO1B抗体
    参阅全部 CORO1B 一抗
  • 描述
    兔多克隆抗体to CORO1B
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 450 and 489 of human CORO1B (NP_065174.1).

  • 阳性对照
    • Human Controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Stomach Carcinoma and Skin Squamous Cell Carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
    • 序列相似性Belongs to the WD repeat coronin family.
      Contains 5 WD repeats.
    • 翻译后修饰Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
    • 细胞定位Cytoplasm > cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
    • Information by UniProt
    • 数据库链接
    • 别名
      • COR1B_HUMAN antibody
      • CORO 1B antibody
      • CORO1B antibody
      • Coronin 1B antibody
      • Coronin 2 antibody
      • Coronin actin binding protein 1B antibody
      • Coronin-1B antibody
      • Coronin-2 antibody
      • Coronin1B antibody
      • Coronin2 antibody
      • DKFZP762I166 antibody
      • OTTHUMP00000236823 antibody
      see all

    Anti-CORO1B antibody 图像

    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB detection.
    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human stomach carcinoma by Immunohistochemistry, using DAB detection.

    Anti-CORO1B antibody (ab84558)参考文献

    ab84558 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84558.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"