概述

  • 产品名称Anti-COPG抗体
    参阅全部 COPG 一抗
  • 描述
    兔多克隆抗体to COPG
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MLKKFDKKDE ESGGGSNPFQ HLEKSAVLQE ARVFNETPIN PRKCAHILTK) of Human COPG (NP_057212).

  • 阳性对照
    • THP1 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab102044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 98 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis.
  • 序列相似性Belongs to the COPG family.
    Contains 4 HEAT repeats.
  • 细胞定位Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Coat protein gamma cop antibody
    • Coatomer protein complex, subunit gamma 1 antibody
    • coatomer protein complex, subunit gamma antibody
    • Coatomer subunit gamma antibody
    • Coatomer subunit gamma-1 antibody
    • COP antibody
    • COPG1 antibody
    • COPG1_HUMAN antibody
    • FLJ21068 antibody
    • Gamma coat protein antibody
    • Gamma COP antibody
    • Gamma-1-coat protein antibody
    • Gamma-1-COP antibody
    see all

Anti-COPG antibody 图像

  • Anti-COPG antibody (ab102044) at 1 µg/ml + THP1 cell lysate at 10 µg

    Predicted band size : 98 kDa

Anti-COPG antibody (ab102044)参考文献

ab102044 has not yet been referenced specifically in any publications.

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