Anti-Contactin 6抗体(ab49207)

概述

  • 产品名称Anti-Contactin 6抗体
    参阅全部 Contactin 6 一抗
  • 描述
    兔多克隆抗体to Contactin 6
  • 特异性Specificity of this product was demonstrated by immunohistochemistry where neurons were intensely stained in rat dorsal root ganglia. Oligodendrocytes in the rat trigeminal nerve root are also stained.
  • 经测试应用适用于: ELISA, IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    A peptide corresponding to an antigenic region within the carboxy-terminal domain of the rat Contactin 6 protein. This peptide was conjugated to carrier protein to enhance the immunological response.

性能

应用

Our Abpromise guarantee covers the use of ab49207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-Fr
  • 应用说明1 site ELISA: 1/5000.
    IHC-Fr: 1/4000.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
    • 组织特异性Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
    • 序列相似性Belongs to the immunoglobulin superfamily. Contactin family.
      Contains 4 fibronectin type-III domains.
      Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CNTN 6 antibody
      • CNTN6 antibody
      • CNTN6_HUMAN antibody
      • Contactin 6 precursor antibody
      • Contactin-6 antibody
      • Contactin6 antibody
      • hNB 3 antibody
      • hNB-3 antibody
      • hNB3 antibody
      • MGC133256 antibody
      • NB 3 antibody
      • NB3 antibody
      • Neural adhesion molecule antibody
      • Neural recognition molecule NB 3 antibody
      • Neural recognition molecule NB-3 antibody
      see all

    Anti-Contactin 6 antibody (ab49207)参考文献

    ab49207 has not yet been referenced specifically in any publications.

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