Anti-Constitutive androstane receptor抗体(ab83850)


  • 产品名称
    Anti-Constitutive androstane receptor抗体
    参阅全部 Constitutive androstane receptor 一抗
  • 描述
    兔多克隆抗体to Constitutive androstane receptor
  • 经测试应用
    适用于: IHC-P, WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (PVFRSLPIED QISLLKGAAV EICHIVLNTT FCLQTQNFLC GPLRYTIEDG) of human Constitutive androstane receptor (NP_001070939).

  • 阳性对照
    • Jurkat cell lysate.



Our Abpromise guarantee covers the use of ab83850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.


  • 功能
    Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
  • 组织特异性
    Predominantly expressed in liver.
  • 序列相似性
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域
    Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.
  • 翻译后修饰
    Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation.
  • 细胞定位
    Nucleus. Cytoplasm. Cytoplasm > cytoskeleton. Recruited to the cytoplasm by DNAJC7.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAR antibody
    • CAR BETA antibody
    • CAR1 antibody
    • CARA antibody
    • Constitutive activator of retinoid response antibody
    • constitutive active receptor antibody
    • Constitutive active response antibody
    • constitutive androstane nuclear receptor variant 2 antibody
    • constitutive androstane nuclear receptor variant 3 antibody
    • constitutive androstane nuclear receptor variant 4 antibody
    • constitutive androstane nuclear receptor variant 5 antibody
    • Constitutive androstane receptor antibody
    • MB67 antibody
    • MGC97144 antibody
    • NR1I3 antibody
    • NR1I3_HUMAN antibody
    • Nuclear receptor subfamily 1 group I member 3 antibody
    • orphan nuclear hormone receptor antibody
    • Orphan nuclear receptor MB67 antibody
    • Orphan nuclear receptor NR1I3 antibody
    see all

Anti-Constitutive androstane receptor antibody 图像

  • Anti-Constitutive androstane receptor antibody (ab83850) at 1 µg/ml + Jurkat cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 31 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon tissue labelling Constitutive androstane receptor with ab83850 at 5.0µg/ml.

Anti-Constitutive androstane receptor antibody (ab83850)参考文献

ab83850 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83850.
Please use the links above to contact us or submit feedback about this product.