概述

  • 产品名称
  • 描述
    兔多克隆抗体to COMT
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH from the C terminal domain of Human COMT.

  • 阳性对照
    • Human adrenal and liver tissues.

性能

应用

Our Abpromise guarantee covers the use of ab118888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 - 7.5 µg/ml.

靶标

  • 功能
    Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
  • 组织特异性
    Brain, liver, placenta, lymphocytes and erythrocytes.
  • 序列相似性
    Belongs to the mammalian catechol-O-methyltransferase family.
  • 翻译后修饰
    The N-terminus is blocked.
  • 细胞定位
    Cytoplasm and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Catechol O methyltransferase antibody
    • Catechol O-methyltransferase antibody
    • COMT antibody
    • COMT_HUMAN antibody
    • EC 2.1.1.6 antibody
    see all

Anti-COMT antibody 图像

  • ab118888, at 7.5 µg/ml, staining COMT in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
  • ab118888, at 7.5 µg/ml, staining COMT in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

Anti-COMT antibody (ab118888)参考文献

ab118888 has not yet been referenced specifically in any publications.

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