Anti-Complex III Immunocapture抗体[11A51H12] (ab109862)

概述

  • 产品名称Anti-Complex III Immunocapture抗体[11A51H12]
  • 描述
    小鼠单克隆抗体[11A51H12] to Complex III Immunocapture
  • 特异性100 µg ab109862 can capture at least 10 µg Complex III from 1 mg solubilized bovine heart mitochondria.
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human
  • 免疫原

    Bovine Heart Complex III

  • 阳性对照
    • Bovine heart and Human mitochondria
  • 常规说明

    Product was previously marketed under the MitoSciences sub-brand.

性能

应用

Our Abpromise guarantee covers the use of ab109862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. PubMed: 22523357
IP Use at 10-1 µg/mg of lysate.

靶标

  • 相关性Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.

Anti-Complex III Immunocapture antibody [11A51H12] 图像

  • Staining of Complex III Lane 1: 0.1mg of Bovine mitochondria Lane 2: 0.05mg Bovine mitochondria Lane 3: 0.05mg Human mitochondria Immunoprecipitated using ab109862 at 10 µg/mg lysate.

Anti-Complex III Immunocapture antibody [11A51H12] (ab109862)参考文献

This product has been referenced in:
  • Beutner G  et al. Initiation of electron transport chain activity in the embryonic heart coincides with the activation of mitochondrial complex 1 and the formation of supercomplexes. PLoS One 9:e113330 (2014). IP ; Mouse . Read more (PubMed: 25427064) »
  • Jonckheere AI  et al. A complex V ATP5A1 defect causes fatal neonatal mitochondrial encephalopathy. Brain 136:1544-54 (2013). Read more (PubMed: 23599390) »

See all 5 Publications for this product

Product Wall

Thank you for contacting us. Please click these links to find the suitable antibodies. Type the MS code in Abcam search box to get the Abcam catalogue number. Complex I http://www.mitosciences.com/complex_i.html Complex IV http://www.mi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"