Anti-Complex I subunit 8 kDa抗体[17C8E4E11] (ab110245)

概述

  • 产品名称
    Anti-Complex I subunit 8 kDa抗体[17C8E4E11]
  • 描述
    小鼠单克隆抗体[17C8E4E11] to Complex I subunit 8 kDa
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human
  • 免疫原

    Bovine Complex I subunit 8 kDa.

  • 阳性对照
    • Isolated mitochondria from Human, Bovine, Rat and Mouse hearts.
  • 常规说明

    This antibody clone is manufactured by Abcam.

    Product was previously marketed under the MitoSciences sub-brand.

性能

应用

Our Abpromise guarantee covers the use of ab110245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml.

靶标

  • 相关性
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 细胞定位
    Mitochondrial
  • 数据库链接
  • 别名
    • BC021616 antibody
    • CI 23k antibody
    • CI23KD antibody
    • MGC101957 antibody
    • MGC37950 antibody
    • NADH dehydrogenase (ubiquinone) Fe S protein 8, 23kDa (NADH coenzyme Q reductase) antibody
    • NADH ubiquinone oxidoreductase 23 kDa subunit antibody
    • TYKY antibody
    • TYKY subunit antibody
    see all

图片

  • All lanes : Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245) at 1 µg/ml

    Lane 1 : Human heart mitochondria at 10 µg
    Lane 2 : Bovine heart mitochondria at 4 µg
    Lane 3 : Rat heart mitochondria at 10 µg
    Lane 4 : Mouse heart mitochondria at 10 µg

实验方案

文献

This product has been referenced in:
  • Hauser DN  et al. Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. PLoS One 9:e94646 (2014). WB ; Mouse . Read more (PubMed: 24722488) »
  • Thomas RR  et al. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18 (2011). Read more (PubMed: 20727424) »

See all 9 Publications for this product

客户评价及客户问答

Thank you for your enquiry.

We did some workwith our sister companyMitoSciences trying to identify the target of this antibody and so far only managed to narrow down the targets within NDUFA5 and NDUFS6. It may be that we do further work on ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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