Anti-Complement factor B抗体[M13/12] (ab106139)

概述

  • 产品名称
    Anti-Complement factor B抗体[M13/12]
    参阅全部 Complement factor B 一抗
  • 描述
    小鼠单克隆抗体[M13/12] to Complement factor B
  • 特异性
    ab106139 recognizes complement factor B/Bb
  • 经测试应用
    适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Complement factor B/Bb

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    M13/12
  • 同种型
    IgG1

应用

Our Abpromise guarantee covers the use of ab106139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 86 kDa.
IP Use at an assay dependent dilution.

靶标

  • 相关性
    Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
  • 细胞定位
    Plasma membrane and Secreted
  • 数据库链接
  • 别名
    • C3/C5 convertase antibody
    • Complement factor B antibody
    • Glycine-rich beta glycoprotein antibody
    • PBF2 antibody
    • Properdin factor B antibody
    see all

文献

This product has been referenced in:
  • Oppermann M  et al. Elevated plasma levels of the immunosuppressive complement fragment Ba in renal failure. Kidney Int 40:939-47 (1991). Read more (PubMed: 1837062) »
  • Oppermann M  et al. Quantitation of components of the alternative pathway of complement (APC) by enzyme-linked immunosorbent assays. J Immunol Methods 133:181-90 (1990). Read more (PubMed: 2146321) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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