Anti-Complement factor 8 beta抗体(ab111700)

概述

  • 产品名称
    Anti-Complement factor 8 beta抗体
    参阅全部 Complement factor 8 beta 一抗
  • 描述
    兔多克隆抗体to Complement factor 8 beta
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 412-563 of Human Complement factor 8 beta (AAI30576).

  • 阳性对照
    • HeLa, HepG2 and HCT116 whole cell lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1% BSA, 20% Glycerol, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111700 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 67 kDa.

靶标

  • 功能
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
  • 疾病相关
    Defects in C8B are a cause of complement component 8 deficiency type 2 (C8D2) [MIM:120960]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
  • 序列相似性
    Belongs to the complement C6/C7/C8/C9 family.
    Contains 1 EGF-like domain.
    Contains 1 LDL-receptor class A domain.
    Contains 1 MACPF domain.
    Contains 2 TSP type-1 domains.
  • 翻译后修饰
    N-glycosylated; contains one or two bound glycans. Not O-glycosylated.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C8b antibody
    • CO8B_HUMAN antibody
    • Complement component 8 beta polypeptide antibody
    • Complement component 8 subunit beta antibody
    • Complement component C8 beta chain antibody
    see all

图片

  • Anti-Complement factor 8 beta antibody (ab111700) at 1/5000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 67 kDa

实验方案

文献

ab111700 has not yet been referenced specifically in any publications.

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