Colchicine from Colchicum autumnale (ab120663)

概述

  • 产品名称
    Colchicine from Colchicum autumnale
  • 描述
    Inhibitor of microtubule formation
  • 生物学描述
    Inhibitor of microtubule formation (Ki = 2.1 μM). Antimitotic, anti-inflammatory and antifibrotic activity. Unable to cross the blood-brain barrier.
  • 纯度
    > 99%
  • 常规说明

    Light sensitive

性能

文献

This product has been referenced in:
  • Bhattacharyya B  et al. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin. Med Res Rev 28:155-83 (2008). Read more (PubMed: 17464966) »
  • Perez-Ramirez B  et al. Stoichiometric and substoichiometric inhibition of tubulin self-assembly by colchicine analogues. Biochemistry 35:3277-85 (1996). Read more (PubMed: 8605164) »
  • Cramer SF  et al. The mystique of the mistake. With proposed standards for validating proficiency tests in anatomic pathology. Am J Clin Pathol 96:774-7 (1991). Read more (PubMed: 1746496) »

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