Anti-COL4A3BP抗体(ab77186)

概述

  • 产品名称Anti-COL4A3BP抗体
    参阅全部 COL4A3BP 一抗
  • 描述
    山羊多克隆抗体to COL4A3BP
  • 特异性ab77186 is expected to recognise both reported isoforms (NP_005704.1 and NP_112729.1).
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Horse, Chicken, Cow, Dog, Human, Chimpanzee, Orangutan
  • 免疫原

    Synthetic peptide:

    DHDSAPLNNRC

    , from the internal region of Human COL4A3BP protein sequence (NP_005704.1; NP_112729.1).

  • 阳性对照
    • Mouse heart lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab77186 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 71 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May mediate the intracellular trafficking of ceramide in a non-vesicular manner.
    • 组织特异性Widely expressed.
    • 序列相似性Contains 1 PH domain.
      Contains 1 START domain.
    • 结构域The START domain recognizes ceramide and mediates the intermembrane transfer of ceramide.
      The PH domain targets the Golgi apparatus.
      The FFAT motif is required for interaction with VAPA and VAPB.
    • 翻译后修饰Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity.
    • 细胞定位Cytoplasm. Golgi apparatus. Endoplasmic reticulum. Preferentially localized to the Golgi apparatus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha 3 type IV collagen binding protein antibody
      • C43BP_HUMAN antibody
      • Ceramide transfer protein antibody
      • Ceramide transporter antibody
      • CERT antibody
      • Cert protein antibody
      • CERTL antibody
      • col4a3bp antibody
      • Collagen type IV alpha 3 (Goodpasture antigen) binding protein antibody
      • Collagen type IV alpha 3 binding protein antibody
      • Collagen type IV alpha-3-binding protein antibody
      • FLJ20597 antibody
      • Goodpasture antigen binding protein antibody
      • Goodpasture antigen-binding protein antibody
      • GPBP antibody
      • hCERT antibody
      • Lipid transfer protein CERTL antibody
      • Procollagen type IV alpha 3 (Goodpasture antigen) binding protein antibody
      • StAR related lipid transfer (START) domain containing 11 antibody
      • StAR related lipid transfer protein 11 antibody
      • StAR-related lipid transfer protein 11 antibody
      • StARD 11 antibody
      • StARD11 antibody
      • START domain containing 11 antibody
      • START domain containing protein 11 antibody
      • START domain-containing protein 11 antibody
      see all

    Anti-COL4A3BP antibody 图像

    • Anti-COL4A3BP antibody (ab77186) at 0.5 µg/ml + mouse heart lysate in RIPA buffer at 35 µg

      Predicted band size : 71 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 26 kDa. We are unsure as to the identity of these extra bands.

    Anti-COL4A3BP antibody (ab77186)参考文献

    ab77186 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us with your question about ab77186.
    Ab77186 is predicted to work with chicken samples based on sequence homology, though we don't know for sure until it is tested. It is quite possible that the antibody will work in tissu...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"