概述

  • 产品名称Anti-COL19A1抗体
  • 描述
    兔多克隆抗体to COL19A1
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: VTVRDKTEES CPILRIEGHQ LTYDNINKLE VSGFDLGDSF SLRRAFCESD KTCFKLGSAL LIRDTIKIFP KGLPEEYSVA AMFRVRRNAK KERWFLWQVL, corresponding to amino acids of Human COL19A1.

  • 阳性对照
    • Human urinary bladder tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab122793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.
  • 组织特异性Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
  • 序列相似性Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
    Contains 1 TSP N-terminal (TSPN) domain.
  • 结构域The numerous interruptions in the triple helix may make this molecule either elastic or flexible.
  • 翻译后修饰Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • COJA1_HUMAN antibody
    • COL19A1 antibody
    • COL9A1L antibody
    • Collagen alpha-1(XIX) chain antibody
    • Collagen alpha-1(Y) chain antibody
    • D6S228E antibody
    see all

Anti-COL19A1 antibody 图像

  • Immunofluorescent staining of Human cell line A-431 shows positivity in cytoplasm and cell junctions. Recommended concentration of ab122793 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122793, at 1/200 dilution, staining COL19A1 in paraffin-embedded Human urinary bladder tissue by Immunohistochemistry.

Anti-COL19A1 antibody (ab122793)参考文献

ab122793 has not yet been referenced specifically in any publications.

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