概述

  • 产品名称Anti-COL16A1抗体
  • 描述
    兔多克隆抗体to COL16A1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen: FVSCIFPVPQ LFDLRWHKLM LSVAGRVASV HVDCSSASSQ PLGPRRPMRP VGHVFLGLDA EQGKPVSFDL QQVHIYCDPE LVLEEGCCEL LP, corresponding to amino acids 153-244 of Human COL16A1.

  • 阳性对照
    • Human gall bladder tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121930 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.
  • 组织特异性In papillary dermis, is a component of specialized fibrillin-1-containing microfibrils, whereas in territorial cartilage matrix, it is localized to a discrete population of thin, weakly banded collagen fibrils in association with other collagens (at protein level). In the placenta, where it is found in the amnion, a membranous tissue lining the amniotic cavity. Within the amnion, it is found in an acellular, relatively dense layer of a complex network of reticular fibers. Also located to a fibroblast layer beneath this dense layer. Exists in tissues in association with other types of collagen.
  • 序列相似性Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
    Contains 1 TSP N-terminal (TSPN) domain.
  • 发展阶段Transiently elevated expression during gestation, and decrease at term.
  • 结构域This sequence defines eighteen different domains, nine triple-helical domains (COL9 to COL1) and ten non-triple-helical domains (NC10 to NC1). The numerous interruptions in the triple helix may make this molecule either elastic or flexible.
  • 翻译后修饰Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
    Glycosylated.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 447AA antibody
    • Alpha 1 type XVI collagen antibody
    • COGA1_HUMAN antibody
    • Col16a1 antibody
    • Collagen alpha-1(XVI) chain antibody
    • Collagen, type XVI, alpha 1 antibody
    • FP1572 antibody
    see all

Anti-COL16A1 antibody 图像

  • ab121930, at 1/2500 dilution, staining COL16A1 in paraffin embedded Human gall bladder tissue by Immunohistochemistry.
  • Immunohistochemical staining of Human placenta shows strong positivity in trophoblastic cells using ab121930

Anti-COL16A1 antibody (ab121930)参考文献

ab121930 has not yet been referenced specifically in any publications.

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