概述

  • 产品名称Anti-CNTROB抗体
    参阅全部 CNTROB 一抗
  • 描述
    兔多克隆抗体to CNTROB
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human CNTROB.

  • 阳性对照
    • Human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab110916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
  • 组织特异性Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
  • 发展阶段Preferentially incorporated into the newly assembled daughter centriole during centriole assembly at the late G1 or early S phase. Remains in the daughter centrioles throughout the cell cycle. At the next cycle of centriole duplication, its amount on the original daughter centriole eventually decreases.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm > cytoskeleton > centrosome > centriole. Centriole-associated, asymmetrically localizes to the daughter centriole.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9830165K03Rik antibody
    • Centrobin antibody
    • centrobin, centrosomal BRCA2 interacting protein antibody
    • Centrosomal BRCA2 interacting protein antibody
    • Centrosomal BRCA2-interacting protein antibody
    • CNTRB_HUMAN antibody
    • Cntrob antibody
    • LIP8 antibody
    • LYST interacting protein 8 antibody
    • LYST-interacting protein 8 antibody
    • LYST-interacting protein LIP8 antibody
    • PP1221 antibody
    • RGD1307488 antibody
    • RP23 26L6.9 antibody
    see all

Anti-CNTROB antibody 图像

  • ab110916 at 1/50 dilution staining CNTROB in paraffin-embedded Human Brain tissue by Immunohistochemistry. The picture on the right is treated with the synthesized peptide.

Anti-CNTROB antibody (ab110916)参考文献

ab110916 has not yet been referenced specifically in any publications.

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