概述

  • 产品名称Anti-CNOT4抗体
    参阅全部 CNOT4 一抗
  • 描述
    兔多克隆抗体to CNOT4
  • 特异性Detects endogenous levels of total CNOT4 protein
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthesized peptide derived from an internal sequence of human CNOT4.

  • 阳性对照
    • Extracts from Jurkat or K562 cells; human testis tissue

性能

应用

Our Abpromise guarantee covers the use of ab110013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 63 kDa.
IHC-P 1/50 - 1/100.

靶标

  • 功能Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 C3H1-type zinc finger.
    Contains 1 RING-type zinc finger.
    Contains 1 RRM (RNA recognition motif) domain.
  • 翻译后修饰Autoubiquitinated.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCR4 NOT transcription complex subunit 4 antibody
    • CCR4-associated factor 4 antibody
    • CCR4-NOT transcription complex subunit 4 antibody
    • CLONE243 antibody
    • CNOT 4 antibody
    • Cnot4 antibody
    • CNOT4_HUMAN antibody
    • E3 ubiquitin-protein ligase CNOT4 antibody
    • NOT 4 antibody
    • NOT4 (negative regulator of transcription 4 yeast) homolog antibody
    • NOT4 antibody
    • NOT4H antibody
    • Potential transcriptional repressor NOT4Hp antibody
    see all

Anti-CNOT4 antibody 图像

  • Immunohistochemistry analysis of paraffin embedded human testis tissue, using ab110013 at 1/50. The picture on the right is treated with the synthesized peptide.
  • All lanes : Anti-CNOT4 antibody (ab110013) at 1/500 dilution

    Lane 1 : extracts from K562 cells (5-30 ug) with no immunizing peptide
    Lane 2 : extracts from Jurkat cells (5-30 ug) with no immunizing peptide
    Lane 3 : extracts from K562 cells (5-30 ug) with immunizing peptide (5-10 ug)


    Predicted band size : 63 kDa

Anti-CNOT4 antibody (ab110013)参考文献

ab110013 has not yet been referenced specifically in any publications.

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