Anti-CNOT2抗体(ab90703)

概述

• 产品名称
  Anti-CNOT2抗体
  参阅全部 CNOT2 一抗
• 描述
  兔多克隆抗体to CNOT2
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Chimpanzee, Zebrafish
• 免疫原

  Synthetic peptide corresponding to a region within internal amino acids 252 - 301 (LAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS N) of Human CNOT2 (NP_055330).

• 阳性对照
  • THP-1 cell lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• 存储溶液
  Preservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Mediator Complex

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • THP1 nuclear extract lysate (ab14900)

应用

靶标

• 功能
  The CCR4-NOT complex functions as general transcription regulation complex.
• 组织特异性
  Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.
• 序列相似性
  Belongs to the CNOT2/3/5 family.
• 翻译后修饰
  Phosphorylated upon DNA damage, probably by ATM or ATR.
• 细胞定位
  Cytoplasm. Nucleus.

• Target information above from: UniProt accession Q9NZN8 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 396117 Chicken
  • Entrez Gene: 4848 Human
  • Entrez Gene: 72068 Mouse
  • Entrez Gene: 299805 Rat
  • Omim: 604909 Human
  • SwissProt: Q9NZN8 Human
  • SwissProt: Q3TIJ0 Mouse
  • SwissProt: Q5CZY5 Mouse

  • SwissProt: Q8C5L3 Mouse
  • SwissProt: Q5PPJ8 Rat
  • Unigene: 133350 Human
  • Unigene: 351553 Mouse
  • Unigene: 99836 Rat

  see all
• 别名
  • CCR4 associated factor 2 antibody
  • CCR4 NOT transcription complex subunit 2 antibody
  • CCR4-associated factor 2 antibody

  • CCR4-NOT transcription complex subunit 2 antibody
  • CDC36 antibody
  • CNOT2 antibody
  • CNOT2_HUMAN antibody
  • HSPC131 antibody
  • MSTP046 antibody
  • Negative regulator of transcription 2 antibody
  • NOT2 (negative regulator of transcription 2 yeast) homolog antibody
  • NOT2 antibody
  • NOT2H antibody

  see all

实验方案

• Western blot protocols