功能Involved in the selective transport and maturation of TGF-alpha family proteins.
组织特异性Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver.
序列相似性Belongs to the cornichon family.
细胞定位Endoplasmic reticulum membrane. Golgi apparatus membrane. Located primarily in the ER; may cycle between the ER and the Golgi apparatus.