概述

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab48066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • CCHC type zinc finger nucleic acid binding protein
    • Cellular nucleic acid binding protein
    • Cellular nucleic acid-binding protein
    • CNBP
    • CNBP_HUMAN
    • CNBP1
    • DM2
    • Erythroid differentiation related
    • PROMM
    • Proximal myotonic myopathy nucleic acid binding protein
    • RNF163
    • Sterol regulatory element binding protein
    • ZCCHC22
    • Zinc finger protein 273
    • Zinc finger protein 9
    • Zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
    • ZNF9
    see all
  • 功能
    Single stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.
  • 组织特异性
    Present in all tissues examined.
  • 疾病相关
    Defects in CNBP are the cause of dystrophia myotonica type 2 (DM2) [MIM:602668]; also known as proximal myotonic myopathy (PROMM). A multisystem disease characterized by the association of proximal muscle weakness with myotonia, cardiac manifestations and cataract. Additional features can include hyperhidrosis, testicular atrophy, insulin resistance and diabetes and central nervous system anomalies in rare cases. Note=The causative mutation is a CCTG expansion (mean approximately 5000 repeats) located in intron 1 of the CNBP gene.
  • 序列相似性
    Contains 7 CCHC-type zinc fingers.
  • 细胞定位
    Cytoplasm. Endoplasmic reticulum.
  • Information by UniProt

文献

ab48066 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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