概述

  • 产品名称Anti-CMAS抗体
    参阅全部 CMAS 一抗
  • 描述
    兔多克隆抗体to CMAS
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 69-384 of Human CMAS (NP_061156)

  • 阳性对照
    • 293T and HeLaS3 cells

性能

应用

Our Abpromise guarantee covers the use of ab97655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
  • 组织特异性Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
  • 通路Amino-sugar metabolism; N-acetylneuraminate metabolism.
  • 序列相似性Belongs to the CMP-NeuNAc synthase family.
  • 结构域The BC2 (basic cluster 2) motif is necessary and sufficient for the nuclear localization and contains the catalytic active site. The localization in the nucleus is however not required for the enzyme activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CMAS antibody
    • CMP N acetylneuraminic acid synthase antibody
    • CMP Neu5Ac synthetase antibody
    • CMP NeuNAc synthetase antibody
    • CMP sialic acid synthetase antibody
    • CMP-N-acetylneuraminic acid synthase antibody
    • CMP-N-acetylneuraminic acid synthetase antibody
    • CMP-NeuNAc synthase antibody
    • CSS antibody
    • Cytidine 5' monophosphate N acetylneuraminic acid synthetase antibody
    • Cytidine 5-prime-monophosphate N-acetylneuraminic acid synthetase antibody
    • Cytidine monophosphate N acetylneuraminic acid synthetase antibody
    • N acylneuraminate cytidylyltransferase antibody
    • N-acylneuraminate cytidylyltransferase antibody
    • NEUA_HUMAN antibody
    see all

Anti-CMAS antibody 图像

  • All lanes : Anti-CMAS antibody (ab97655) at 1/1500 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : HeLaS3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CMAS antibody (ab97655) at 1/200 dilution. Lower panel is merged with DNA probe.

Anti-CMAS antibody (ab97655)参考文献

ab97655 has not yet been referenced specifically in any publications.

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