概述

  • 产品名称Anti-CMAS抗体
    参阅全部 CMAS 一抗
  • 描述
    小鼠单克隆抗体to CMAS
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: EGYDSVFSVV RRHQFRWSEI QKGVREVTEP LNLNPAKRPR RQDWDGELYE NGSFYFAKRH LIEMGYLQGG KMAYYEMRAE HSVDIDVDID WPIAEQRVLR , corresponding to amino acids 164-264 of Human CMAS

性能

应用

Our Abpromise guarantee covers the use of ab57454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
    • 组织特异性Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
    • 通路Amino-sugar metabolism; N-acetylneuraminate metabolism.
    • 序列相似性Belongs to the CMP-NeuNAc synthase family.
    • 结构域The BC2 (basic cluster 2) motif is necessary and sufficient for the nuclear localization and contains the catalytic active site. The localization in the nucleus is however not required for the enzyme activity.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CMAS antibody
      • CMP N acetylneuraminic acid synthase antibody
      • CMP Neu5Ac synthetase antibody
      • CMP NeuNAc synthetase antibody
      • CMP sialic acid synthetase antibody
      • CMP-N-acetylneuraminic acid synthase antibody
      • CMP-N-acetylneuraminic acid synthetase antibody
      • CMP-NeuNAc synthase antibody
      • CSS antibody
      • Cytidine 5' monophosphate N acetylneuraminic acid synthetase antibody
      • Cytidine 5-prime-monophosphate N-acetylneuraminic acid synthetase antibody
      • Cytidine monophosphate N acetylneuraminic acid synthetase antibody
      • N acylneuraminate cytidylyltransferase antibody
      • N-acylneuraminate cytidylyltransferase antibody
      • NEUA_HUMAN antibody
      see all

    Anti-CMAS antibody 图像

    • CMAS antibody (ab57454) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.


    • Predicted band size : 48 kDa
      CMAS antibody (ab57454) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-CMAS antibody (ab57454)参考文献

    ab57454 has not yet been referenced specifically in any publications.

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